CBD universe

There are several types of cannabis plant: Cannabis Sativa, Cannabis Indica and Cannabis Rudelis. Hemp and marijuana are often confused because they are 2 species of the Cannabis Sativa plant.

The main difference between hemp and marijuana is the different level of CBD (cannabidiol) and THC (tetrahydrocannabinol) in their content, the main and most studied cannabinoids of the cannabis plant.

Hemp naturally contains a large amount of CBD and only traces of THC, being ideal to benefit from the medicinal remedies of the cannabis plant without the psychoactive effect (“high”), while marijuana contains a large amount of THC and only traces of CBD, being generally known for its recreational effects.

In conclusion, we are talking about marijuana in recreational contexts in which users pursue the psychotropic sensation, while hemp is at the complete opposite pole, being studied for its therapeutic properties on the body.

Cannabinoids are the active compounds found in the cannabis plant. There are more than 100 different cannabinoids, and the most studied are cannabidiol (CBD) and tetrahydrocannabinol (THC). At the same time, specialized literature and studies in the field also mention other cannabinoids such as CBDa (cannabidiol acid), CBGa (cannabigerolic acid), CBG (cannabigerol), CBN (cannabinol), CBC (cannabichromene), etc.

Cannabinoids produced from plants, such as CBD, are known as phytocannabinoids and represent one of the three categories of cannabinoids currently being studied. The other two categories are endogenous cannabinoids, produced naturally by the human and animal body (eg anadamide, 2-AG) and synthetic cannabinoids, produced in the laboratory.

Thus, living organisms (plants, animals and humans) are the only natural resources of cannabinoids.

THC (tetrahydrocannabinol) is the psychoactive component of the cannabis high (the one that gives the feeling of dizziness, “high”) found in up to 30% of the marijuana plant (not the hemp plant). Thus, THC is responsible for the euphoria typically associated with the recreational use of marijuana. Consumed in large quantities and repeatedly, THC can lead to changes in the way the brain perceives reality and to the establishment of addiction in the body.

Discovered in 1988, the endocannabinoid system (ES) is probably one of the most important systems in the human body because it is responsible for maintaining optimal parameters of all other systems in the body, as well as its normal functions (homeostasis), from temperature body and blood pH, up to blood pressure and blood sugar level.

The components of SE are: cannabinoid receptors (CB1 and CB2), endogenous cannabinoids (which stimulate SE by interacting with receptors) and enzymes (responsible for destroying endocannabinoids once they have completed their tasks).

CB1 receptors are mainly located in the central nervous system and are responsible for certain mental and psychological processes: hippocampus (memory), cerebral cortex (cognition), cerebellum (motor coordination), basal ganglia (movement), hypothalamus (appetite) and cerebral amygdala ( emotions). CB2 receptors have an important role in modulating pain, inflammation and the optimal function of the immune system.

The cannabinoids in the cannabis plant interact with these receptors as well. 

CBD Full Spectrum contains all the beneficial natural compounds present in the cannabis plant.

These are cannabinoids (CBD, THC, etc.), terpenes (a class of aromatic substances present in a wide variety of plants and essential oils that protect plants against bacteria, fungi and pests and have the potential to boost mood, immune function, appetite and sleep) and flavonoids (a group of compounds present in certain plants, fruits, vegetables and foods with antioxidant, anti-inflammatory and anti-carcinogenic properties that ensure good protection of the nervous and cardiovascular system).

CBD Broad Spectrum contains all the components of the cannabis plant mentioned above, with the exception of THC.

CBD Isolate contains only CBD and is often found in the form of crystals or powder.

In 2005, a study concluded that a Full Spectrum CBD oil has greater medicinal properties than isolated CBD. Since it contains all the cannabinoids and other compounds of the cannabis plant, a beneficial therapeutic synergy is obtained called the entourage effect.

	FULL SPECTRUM	BROAD SPECTRUM	ISOLATE
CBD
THC
TERPENES
FLAVONOIDS

The relationship between cannabinoids, terpenes and flavonoids can be illustrated by the jar below, which will play the role of hemp plants.

First, we fill that jar with stones; these represent cannabinoids, the largest group of compounds – Later, we use smaller stones to fill the gaps created; these are the terpenes. Finally, to fill the jar, we pour sand, which illustrates the flavonoids and other essential compounds.

We are confident in the promising potential it has on the health of the human body. For this reason, we created a hemp oil formula with CBD, the most well-known and studied cannabinoid, whose effects have been confirmed by multiple studies on various ailments. To potentiate the absorption and effects of the final product, we added additional amounts of cannabigerolic acid (CBGa) and cannabidiol acid (CBDa), the first naturally occurring compounds in the cannabis plant.

Thus, our formula respects the related provisions in force and ensures the presence of the entourage effect (for explanations regarding the entourage effect, see point 7).

CBGa or cannabigerolic acid is considered the “mother” cannabinoid, the precursor to all other cannabinoids present in the cannabis plant. In the early stages of life, the cannabis plant has a high content of CBGa, and as it matures, CBGa turns into other cannabinoids such as CBD and THC.

While CBD and THC are found in proportions of 25-30% in the cannabis plant, CBGa is a rare cannabinoid, found in proportions of 1%.

Currently, studies aimed at epilepsy patients have suggested a superior efficiency of CBGa compared to CBD.

CBDa or cannabidiol acid is the first natural compound that appears in the mature hemp plant and from which, at high temperatures, CBD is obtained through the procedure known as decarboxylation.

According to the studies carried out so far, the presence of CBDa together with CBD potentiates the effects of the latter and the interaction with a series of receptors in the body responsible for memory, mood, sleep, nausea and in infamy.

The beneficial effects of the hemp plant are multiplied when all the compounds of the cannabis plant (cannabinoids, terpenes and flavonoids) are administered together. The entourage effect represents the therapeutic synergy of these compounds.

Thus, although each compound has its own beneficial effects, for maximum effects it is recommended to consume a full-spectrum product, complying with the related provisions in force (for the legislative regime of THC, see point 3). HempAID products were created based on a formula that ensures the presence of the entourage effect (Extended Broad Spectrum).

This term often found in specialized literature defines the rate of absorption of CBD in the body depending on the mode of administration. Thus, clinical studies conclude that the most effective method of administration is sublingual (under the tongue), in the form of CBD oil. The effect on the body is established approximately 20 minutes after administration and has an effect of up to 6 hours.

Other forms of CBD administration studied in clinical and scientific programs are inhalation, local application or ingestion, each of which has advantages and disadvantages. The studies so far conclude that the most effective form of delivery is through CBD oil.

There are studies according to which the effectiveness of CBD has been proven for a significant number of diseases, conditions and ailments. From chronic conditions like epilepsy and schizophrenia to mild conditions like acne, CBD can be a key ingredient that accompanies or even replaces traditional treatments.

Epilepsy – in the last decade, two CBD-based drugs were approved in the USA by the FDA (Food and Drug Administration), used to treat the symptoms of multiple sclerosis and to combat Dravet and Lennox-Gautaut syndromes, two rare forms of epilepsy. Several clinical studies have shown that CBD can reduce the frequency of epileptic seizures by up to 44% in most patients.

Chronic diseases – There are several studies that show that CBD relieves chronic pain caused by arthritis, multiple sclerosis and other conditions.

Anxiety and depression – in a study with people suffering from social anxiety disorder and phobia, participants had significant reductions in symptoms of anxiety and cognitive impairment.

Insomnia – in many instances, insomnia and sleep-related problems accompany anxiety disorders. In a study targeting a form of pediatric PTSD (Post Traumatic Stress Disorder), CBD was shown to consistently improve sleep quality over a 5-month period in the absence of another pharmaceutical drug.

Acne and other skin problems – Studies have shown that CBD is effective in slowing down and inhibiting the production of sebocytes, the main cause of acne.

Alzheimer’s – Recent studies have shown that CBD reduces or eliminates the impact of inflammation, the accumulation of oxygen and the decline of brain cells, symptoms encountered in the case of this disease.

Autism – A study conducted in Israel concluded that CBD can improve some of the symptoms of people with autism, including seizures, agitation and anger attacks.

Parkinson’s – Parkinson’s is a progressive chronic disease of the nervous system, marked by tremors, muscle stiffness and slow, imprecise movement. Cannabinoids like CBD have been proven to contain effective brain protectors, antioxidants and rich in anti-inflammatory properties beneficial for managing these symptoms.

Addictions (drugs, alcohol, tobacco) – According to studies, CBD can also be used by those who want to overcome addiction to nicotine or opioids, by alleviating withdrawal symptoms.

Schizophrenia / psychosis – Studies have reported significant improvements in these conditions for patients who did not respond to conventional medication and turned to CBD.

Cancer – Nausea and vomiting are two of the most common symptoms of chemotherapy. These symptoms can be so intense that between 25%-50% of patients choose to postpone or even refuse this treatment. Studies have shown that CBD can control and reduce both nausea and vomiting caused by chemotherapy. There are also more and more ongoing studies that suggest that CBD may facilitate the death of cancer cells and slow the spread of aggressive cancer cells in breast cancer.